The Laboratory of Mammary Gland Biology

Publications


2026

Machiela, M.N., Myer, R.G., Quinn, M.J., Webster, H.H., Perez-Hernandez, G., Corl, B.A., Trott, J.F., Hovey, R.C., 2026. Dynamics of mammary cell division during pregnancy and lactation in dairy cows. J Dairy Sci S0022-0302(26)02881-X. https://doi.org/10.3168/jds.2025-28100

Sadovnikova, A., Coley, M., Powell, L., Hoyt-Austin, A., Hedriana, H.L., Kuhn-Riordon, K.M., Hovey, R.C., Slupsky, C.M., Zhang, F., Kapa, N., 2026. Defining lactation outcomes, milk composition, and breastfeeding safety for women with chronic kidney disease: protocol for a prospective observational study. Int Breastfeed J 21. https://doi.org/10.1186/s13006-026-00821-0

Trott, J.F., Falt, T.D., Mosburg, M.M., Moeller, B.C., Solomon, G.M., Hovey, R.C., 2026. Determining the sex of store-bought beef to distinguish between endogenous and exogenous hormone residues. Meat Sci 234, 110040. https://doi.org/10.1016/j.meatsci.2026.110040

2025

Altman, M.D., Mathews, A.T., Rabaglino, M.B., Hovey, R.C., Denicol, A.C., 2025. Canonical prolactin signaling and global mRNA expression in the skin of Holstein heifers carrying the SLICK1 allele of the prolactin receptor gene. J Dairy Sci 108, 4422–4434. https://doi.org/10.3168/jds.2024-25821

Gargiulo, J.I., Garcia, S.C., Hovey, R.C., 2025. Sources of variation underlying the production of lactose by dairy cows. J Dairy Sci 108, 4403–4421. https://doi.org/10.3168/jds.2024-25644

Mosburg, M., Li, Y., Helmes, E., Falt, T.D., Trott, J.F., Solomon, G., Hovey, R.C., Moeller, B.C., 2025. Determination of Hormonal Growth Promotants in Beef Using Liquid Chromatography-Tandem Mass Spectrometry. Drug Test Anal 17, 1237–1251. https://doi.org/10.1002/dta.3827

Thilakaratne, R., Castorina, R., Solomon, G., Mosburg, M.M., Moeller, B.C., Trott, J.F., Falt, T.D., Villegas-Gomez, A., Dodd, K.W., Thomsen, C., English, P., Yang, X., Khan, A., Bradman, A., Hovey, R.C., 2025. Estimated human intake of endogenous and exogenous hormones from beef in the United States. J Expo Sci Environ Epidemiol 35, 362–374. https://doi.org/10.1038/s41370-024-00727-1

2024

Banks, C.M., Trott, J.F., Hovey, R.C., 2024. The prolactin receptor: A cross-species comparison of gene structure, transcriptional regulation, tissue-specificity, and genetic variation. J Neuroendocrinol 36, e13385. https://doi.org/10.1111/jne.13385

Farmer, C., Johannsen, J.C., Gillies, C., Huber, L.-A., Hovey, R.C., 2024. Parity affects mammary development in late-pregnant swine. Transl Anim Sci 8, txae037. https://doi.org/10.1093/tas/txae037

Machiela, M.N., Hovey, R.C., 2024. Intramammary Labeling of Epithelial Cell Division. J Mammary Gland Biol Neoplasia 29, 17. https://doi.org/10.1007/s10911-024-09570-4

2023

Farmer, C., Gillies, C., Johannsen, J.C., Hovey, R.C., Huber, L.-A., 2023. Dietary supplementation with lysine (protein) in late pregnancy does not enhance mammary development in multiparous sows. J Anim Sci 101. https://doi.org/10.1093/jas/skad385

Geiger, A.J., Hovey, R.C., 2023. Development of the mammary glands and its regulation: how not all species are equal. Anim Front 13, 44–54. https://doi.org/10.1093/af/vfad029

Morato, A., Accornero, P., Hovey, R.C., 2023. ERBB Receptors and Their Ligands in the Developing Mammary Glands of Different Species: Fifteen Characters in Search of an Author. J Mammary Gland Biol Neoplasia 28, 10. https://doi.org/10.1007/s10911-023-09538-w

Neville, M.C., Demerath, E.W., Hahn-Holbrook, J., Hovey, R.C., Martin-Carli, J., McGuire, M.A., Newton, E.R., Rasmussen, K.M., Rudolph, M.C., Raiten, D.J., 2023. Parental factors that impact the ecology of human mammary development, milk secretion, and milk composition-a report from “Breastmilk Ecology: Genesis of Infant Nutrition (BEGIN)” Working Group 1. Am J Clin Nutr 117 Suppl 1, S11–S27. https://doi.org/10.1016/j.ajcnut.2022.11.026

2022

Farmer, C., Palin, M.-F., Hovey, R.C., Falt, T.D., Huber, L.-A., 2022. Dietary supplementation with lysine (protein) stimulates mammary development in late pregnant gilts. J Anim Sci 100. https://doi.org/10.1093/jas/skac051

Sadovnikova, A., Garcia, S.C., Trott, J.F., Mathews, A.T., Britton, M.T., Durbin-Johnson, B.P., Hovey, R.C., 2022. Transcriptomic changes underlying glucocorticoid-induced suppression of milk production by dairy cows. Front Genet 13, 1072853. https://doi.org/10.3389/fgene.2022.1072853

Trott, J.F., Schennink, A., Horigan, K.C., Lemay, D.G., Cohen, J.R., Famula, T.R., Dragon, J.A., Hovey, R.C., 2022. Unique Transcriptomic Changes Underlie Hormonal Interactions During Mammary Histomorphogenesis in Female Pigs. Endocrinology 163. https://doi.org/10.1210/endocr/bqab256

2021

Berryhill, G.E., Gloviczki, J.M., Trott, J.F., Kraft, J., Lock, A.L., Hovey, R.C., 2021. In Utero Exposure to trans-10, cis-12 Conjugated Linoleic Acid Modifies Postnatal Development of the Mammary Gland and its Hormone Responsiveness. J Mammary Gland Biol Neoplasia 26, 263–276. https://doi.org/10.1007/s10911-021-09499-y

Hovey, R.C., Koledova, Z., 2021. Evolution and Self-renewal of the Journal of Mammary Gland Biology and Neoplasia. J Mammary Gland Biol Neoplasia 26, 217–220. https://doi.org/10.1007/s10911-021-09500-8

Mathews, A.T., Banks, C.M., Trott, J.F., Sainz, R.D., Farmer, C., Pendergast, I.I., Hovey, R.C., 2021. Metoclopramide induces preparturient, low-level hyperprolactinemia to increase milk production in primiparous sows. Domest Anim Endocrinol 74, 106517. https://doi.org/10.1016/j.domaniend.2020.106517

Sadovnikova, A., Garcia, S.C., Hovey, R.C., 2021a. A Comparative Review of the Extrinsic and Intrinsic Factors Regulating Lactose Synthesis. J Mammary Gland Biol Neoplasia 26, 197–215. https://doi.org/10.1007/s10911-021-09491-6

Sadovnikova, A., Garcia, S.C., Hovey, R.C., 2021b. A Comparative Review of the Cell Biology, Biochemistry, and Genetics of Lactose Synthesis. J Mammary Gland Biol Neoplasia 26, 181–196. https://doi.org/10.1007/s10911-021-09490-7

2020

Caron, A., Palin, M.F., Hovey, R.C., Cohen, J., Laforest, J.P., Farmer, C., 2020. Effects of sustained hyperprolactinemia in late gestation on mammary development of gilts. Domest Anim Endocrinol 72, 106408. https://doi.org/10.1016/j.domaniend.2019.106408

Cohn, B.A., La Merrill, M.A., Krigbaum, N.Y., Wang, M., Park, J.-S., Petreas, M., Yeh, G., Hovey, R.C., Zimmermann, L., Cirillo, P.M., 2020. In utero exposure to poly- and perfluoroalkyl substances (PFASs) and subsequent breast cancer. Reprod Toxicol 92, 112–119. https://doi.org/10.1016/j.reprotox.2019.06.012

Masía, F.M., Lyons, N.A., Piccardi, M., Balzarini, M., Hovey, R.C., Garcia, S.C., 2020. Modeling variability of the lactation curves of cows in automated milking systems. J Dairy Sci 103, 8189–8196. https://doi.org/10.3168/jds.2019-17962

Miszewski, S.G., Trott, J.F., Berryhill, G.E., Tat, L., Green, R., Borowsky, A.D., Miller, J.W., Hovey, R.C., 2020. Folate Deficiency Inhibits Development of the Mammary Gland and its Associated Lymphatics in FVB Mice. J Nutr 150, 2120–2130. https://doi.org/10.1093/jn/nxaa154

2019

Farmer, C., Mathews, A.T., Hovey, R.C., 2019. Using domperidone to induce and sustain hyperprolactinemia in late-pregnant gilts. Domest Anim Endocrinol 66, 14–20. https://doi.org/10.1016/j.domaniend.2018.05.004

2017

Berryhill, Grace E., Lemay, D.G., Trott, J.F., Aimo, L., Lock, A.L., Hovey, R.C., 2017a. The Transcriptome of Estrogen-Independent Mammary Growth in Female Mice Reveals That Not All Mammary Glands Are Created Equally. Endocrinology 158, 3126–3139. https://doi.org/10.1210/en.2017-00395

Berryhill, Grace E., Miszewski, S.G., Trott, J.F., Kraft, J., Lock, A.L., Hovey, R.C., 2017b. Trans-Fatty Acid-Stimulated Mammary Gland Growth in Ovariectomized Mice is Fatty Acid Type and Isomer Specific. Lipids 52, 223–233. https://doi.org/10.1007/s11745-016-4221-2

Berryhill, G. E., Trott, J.F., Derpinghaus, A.L., Hovey, R.C., 2017. TRIENNIAL LACTATION SYMPOSIUM/BOLFA: Dietary regulation of allometric ductal growth in the mammary glands. J Anim Sci 95, 5664–5674. https://doi.org/10.2527/jas2017.1901

Mori, H., Chen, J.Q., Cardiff, R.D., Pénzváltó, Z., Hubbard, N.E., Schuetter, L., Hovey, R.C., Trott, J.F., Borowsky, A.D., 2017. Pathobiology of the 129:Stat1 (-/-) mouse model of human age-related ER-positive breast cancer with an immune infiltrate-excluded phenotype. Breast Cancer Res 19, 102. https://doi.org/10.1186/s13058-017-0892-8

2016

Berryhill, G.E., Brust-Mascher, I., Huynh, J.H., Famula, T.R., Reardon, C., Hovey, R.C., 2016a. A Convenient Method for Evaluating Epithelial Cell Proliferation in the Whole Mammary Glands of Female Mice. Endocrinology 157, 3742–3748. https://doi.org/10.1210/en.2016-1480

Berryhill, G.E., Trott, J.F., Hovey, R.C., 2016b. Mammary gland development–It’s not just about estrogen. J Dairy Sci 99, 875–883. https://doi.org/10.3168/jds.2015-10105

Ji, Y., Rounds, T., Crocker, A., Sussman, B., Hovey, R.C., Kingsley, F., Muss, H.B., Garber, J.E., Wood, M.E., 2016. The Effect of Atorvastatin on Breast Cancer Biomarkers in High-Risk Women. Cancer Prev Res (Phila) 9, 379–384. https://doi.org/10.1158/1940-6207.CAPR-15-0300

Trott, J.F., Kim, J., Abu Aboud, O., Wettersten, H., Stewart, B., Berryhill, G., Uzal, F., Hovey, R.C., Chen, C.-H., Anderson, K., Graef, A., Sarver, A.L., Modiano, J.F., Weiss, R.H., 2016. Inhibiting tryptophan metabolism enhances interferon therapy in kidney cancer. Oncotarget 7, 66540–66557. https://doi.org/10.18632/oncotarget.11658